The answer is normally no. Classes are set for Mon thru Fri. I won't deny there are occasional special occurrences, though.a question for US people, does in college you attend classes even the Saturday? asking for the #Roommates scheduler
Depending what you have in mind, though, you can set class-related things for Saturday. In my time, I would have to attend guest lectures, give a presentation for a project, etc. on Saturday.
However, I do know there were some occasional classes that also had an extra day on Saturday as well. Not many, but some.