Granted, the enemy icons may be represented in a 2D manner, but you can always use colour, or arrow indicators to highlight their facing perhaps?
It could be even a mini puzzle in a way too.
Such as, if you approach the boss from the long typical front, the boss may get a Preliminary round of Alpha Fire, for the heroic approach. Or if you found that secret door, or used another walk way and approach it upfront or another direction, the boss may have no time for an alpha strike.
Just ideas. I replayed PS1 and found the environmental skills unlocked pathways which may give a minor tactical advantage perhaps. Or Disadvantage.
Approach a boss from behind? The Reinforcements will arrive even faster!
Food for thought, etc.
Just thinking what was the point of the Isometric maze, unless it was a automapper/satellite/visual diagram of the dungeon crawl. In which case, that works fine too